| 21/08/2021 | Home | Jack Grealish | Norwich City FC | 22 | 1-0 → 2-0 | 0.18 | 0.55 | 0.77 | Gabriel Jesus |
| 21/08/2021 | Home | Aymeric Laporte | Norwich City FC | 64 | 2-0 → 3-0 | 0.03 | 0.11 | 0.27 | - |
| 21/08/2021 | Home | Raheem Sterling | Norwich City FC | 71 | 3-0 → 4-0 | 0.00 | 0.74 | 0.78 | Gabriel Jesus |
| 21/08/2021 | Home | Riyad Mahrez | Norwich City FC | 84 | 4-0 → 5-0 | 0.00 | 0.59 | 0.90 | Rúben Dias |
| 28/08/2021 | Home | İlkay Gündoğan | Arsenal FC | 7 | 0-0 → 1-0 | 0.25 | 0.19 | 0.67 | Gabriel Jesus |
| 28/08/2021 | Home | Ferrán Torres | Arsenal FC | 12 | 1-0 → 2-0 | 0.18 | 0.54 | 0.70 | - |
| 28/08/2021 | Home | Gabriel Jesus | Arsenal FC | 43 | 2-0 → 3-0 | 0.06 | 0.42 | 0.80 | Jack Grealish |
| 28/08/2021 | Home | Rodri | Arsenal FC | 53 | 3-0 → 4-0 | 0.01 | 0.03 | 0.36 | Ferrán Torres |
| 28/08/2021 | Home | Ferrán Torres | Arsenal FC | 84 | 4-0 → 5-0 | 0.00 | 0.46 | 0.63 | Riyad Mahrez |
| 11/09/2021 | Away | Bernardo Silva | Leicester City FC | 62 | 0-0 → 0-1 | 0.37 | 0.09 | 0.54 | - |
| 25/09/2021 | Away | Gabriel Jesus | Chelsea FC | 53 | 0-0 → 0-1 | 0.35 | 0.03 | 0.14 | João Cancelo |
| 03/10/2021 | Away | Phil Foden | Liverpool FC | 69 | 1-0 → 1-1 | 0.31 | 0.20 | 0.63 | Gabriel Jesus |
| 03/10/2021 | Away | Kevin De Bruyne | Liverpool FC | 81 | 2-1 → 2-2 | 0.33 | 0.10 | 0.03 | - |
| 16/10/2021 | Home | Bernardo Silva | Burnley FC | 12 | 0-0 → 1-0 | 0.26 | 0.67 | 1.00 | - |
| 16/10/2021 | Home | Kevin De Bruyne | Burnley FC | 70 | 1-0 → 2-0 | 0.13 | 0.21 | 0.33 | - |
| 23/10/2021 | Away | İlkay Gündoğan | Brighton & Hove Albion FC | 13 | 0-0 → 0-1 | 0.26 | 0.99 | 0.99 | Bernardo Silva |
| 23/10/2021 | Away | Phil Foden | Brighton & Hove Albion FC | 28 | 0-1 → 0-2 | 0.17 | 0.75 | 0.87 | Jack Grealish |
| 23/10/2021 | Away | Phil Foden | Brighton & Hove Albion FC | 31 | 0-2 → 0-3 | 0.06 | 0.16 | 0.12 | Gabriel Jesus |
| 23/10/2021 | Away | Riyad Mahrez | Brighton & Hove Albion FC | 95 | 1-3 → 1-4 | 0.00 | 0.55 | 0.53 | Phil Foden |
| 06/11/2021 | Away | Eric Bailly (OG) | Manchester United FC | 7 | 0-0 → 0-1 | 0.25 | - | - | - |
| 06/11/2021 | Away | Bernardo Silva | Manchester United FC | 45 | 0-1 → 0-2 | 0.16 | 0.22 | 0.19 | João Cancelo |
| 21/11/2021 | Home | Raheem Sterling | Everton FC | 44 | 0-0 → 1-0 | 0.31 | 0.55 | 0.88 | João Cancelo |
| 21/11/2021 | Home | Rodri | Everton FC | 55 | 1-0 → 2-0 | 0.15 | 0.02 | 0.21 | - |
| 21/11/2021 | Home | Bernardo Silva | Everton FC | 86 | 2-0 → 3-0 | 0.00 | 0.38 | 0.78 | - |
| 28/11/2021 | Home | İlkay Gündoğan | West Ham United FC | 33 | 0-0 → 1-0 | 0.30 | 0.48 | 0.98 | - |
| 28/11/2021 | Home | Fernandinho | West Ham United FC | 90 | 1-0 → 2-0 | 0.03 | 0.14 | 0.34 | İlkay Gündoğan |
| 01/12/2021 | Away | Rúben Dias | Aston Villa FC | 27 | 0-0 → 0-1 | 0.27 | 0.05 | 0.31 | Raheem Sterling |
| 01/12/2021 | Away | Bernardo Silva | Aston Villa FC | 43 | 0-1 → 0-2 | 0.16 | 0.28 | 0.72 | Gabriel Jesus |
| 04/12/2021 | Away | Raheem Sterling | Watford FC | 4 | 0-0 → 0-1 | 0.25 | 0.49 | 0.87 | Phil Foden |
| 04/12/2021 | Away | Bernardo Silva | Watford FC | 31 | 0-1 → 0-2 | 0.17 | 0.07 | 0.03 | - |
| 04/12/2021 | Away | Bernardo Silva | Watford FC | 63 | 0-2 → 0-3 | 0.03 | 0.05 | 0.49 | Kyle Walker |
| 11/12/2021 | Home | Raheem Sterling | Wolverhampton Wanderers FC | 66 | 0-0 → 1-0 | 0.40 | 0.79 | 0.92 | - |
| 14/12/2021 | Home | Phil Foden | Leeds United FC | 8 | 0-0 → 1-0 | 0.26 | 0.13 | 0.17 | - |
| 14/12/2021 | Home | Jack Grealish | Leeds United FC | 13 | 1-0 → 2-0 | 0.18 | 0.22 | 0.07 | Riyad Mahrez |
| 14/12/2021 | Home | Kevin De Bruyne | Leeds United FC | 32 | 2-0 → 3-0 | 0.06 | 0.22 | 0.13 | Rodri |
| 14/12/2021 | Home | Riyad Mahrez | Leeds United FC | 49 | 3-0 → 4-0 | 0.01 | 0.08 | 0.57 | İlkay Gündoğan |
| 14/12/2021 | Home | Kevin De Bruyne | Leeds United FC | 62 | 4-0 → 5-0 | 0.00 | 0.07 | 0.14 | İlkay Gündoğan |
| 14/12/2021 | Home | John Stones | Leeds United FC | 74 | 5-0 → 6-0 | 0.00 | 0.11 | 0.20 | - |
| 14/12/2021 | Home | Nathan Aké | Leeds United FC | 78 | 6-0 → 7-0 | 0.00 | 0.08 | 0.15 | Phil Foden |
| 19/12/2021 | Away | Rúben Dias | Newcastle United FC | 5 | 0-0 → 0-1 | 0.26 | 0.66 | 0.54 | João Cancelo |
| 19/12/2021 | Away | João Cancelo | Newcastle United FC | 27 | 0-1 → 0-2 | 0.18 | 0.06 | 0.26 | Riyad Mahrez |
| 19/12/2021 | Away | Riyad Mahrez | Newcastle United FC | 63 | 0-2 → 0-3 | 0.03 | 0.14 | 0.29 | Oleksandr Zinchenko |
| 19/12/2021 | Away | Raheem Sterling | Newcastle United FC | 86 | 0-3 → 0-4 | 0.00 | 0.74 | 0.93 | Gabriel Jesus |
| 26/12/2021 | Home | Kevin De Bruyne | Leicester City FC | 5 | 0-0 → 1-0 | 0.26 | 0.14 | 0.20 | Fernandinho |
| 26/12/2021 | Home | Riyad Mahrez | Leicester City FC | 14 | 1-0 → 2-0 | 0.18 | 0.79 | 0.98 | - |
| 26/12/2021 | Home | İlkay Gündoğan | Leicester City FC | 21 | 2-0 → 3-0 | 0.06 | 0.20 | 0.90 | - |
| 26/12/2021 | Home | Raheem Sterling | Leicester City FC | 25 | 3-0 → 4-0 | 0.00 | 0.79 | 0.99 | - |
| 26/12/2021 | Home | Aymeric Laporte | Leicester City FC | 69 | 4-3 → 5-3 | 0.13 | 0.08 | 0.73 | Riyad Mahrez |
| 26/12/2021 | Home | Raheem Sterling | Leicester City FC | 87 | 5-3 → 6-3 | 0.00 | 0.71 | 0.59 | Rúben Dias |
| 29/12/2021 | Away | Phil Foden | Brentford FC | 16 | 0-0 → 0-1 | 0.25 | 0.71 | 0.97 | Kevin De Bruyne |
| 01/01/2022 | Away | Riyad Mahrez | Arsenal FC | 57 | 1-0 → 1-1 | 0.29 | 0.79 | 0.99 | - |
| 01/01/2022 | Away | Rodri | Arsenal FC | 93 | 1-1 → 1-2 | 0.63 | 0.13 | 0.67 | - |
| 15/01/2022 | Home | Kevin De Bruyne | Chelsea FC | 70 | 0-0 → 1-0 | 0.42 | 0.05 | 0.31 | João Cancelo |
| 22/01/2022 | Away | Aymeric Laporte | Southampton FC | 65 | 1-0 → 1-1 | 0.28 | 0.28 | 0.24 | Kevin De Bruyne |
| 09/02/2022 | Home | Riyad Mahrez | Brentford FC | 40 | 0-0 → 1-0 | 0.31 | 0.79 | 1.00 | - |
| 09/02/2022 | Home | Kevin De Bruyne | Brentford FC | 69 | 1-0 → 2-0 | 0.13 | 0.09 | 0.16 | - |
| 12/02/2022 | Away | Raheem Sterling | Norwich City FC | 31 | 0-0 → 0-1 | 0.30 | 0.05 | 0.48 | Kyle Walker |
| 12/02/2022 | Away | Phil Foden | Norwich City FC | 48 | 0-1 → 0-2 | 0.16 | 0.41 | 0.60 | - |
| 12/02/2022 | Away | Raheem Sterling | Norwich City FC | 70 | 0-2 → 0-3 | 0.03 | 0.69 | 0.31 | Rúben Dias |
| 12/02/2022 | Away | Raheem Sterling | Norwich City FC | 90 | 0-3 → 0-4 | 0.00 | 0.79 | 0.90 | - |
| 19/02/2022 | Home | İlkay Gündoğan | Tottenham Hotspur FC | 33 | 0-1 → 1-1 | 0.26 | 0.26 | 0.89 | - |
| 19/02/2022 | Home | Riyad Mahrez | Tottenham Hotspur FC | 92 | 1-2 → 2-2 | 0.33 | 0.79 | 0.99 | - |
| 26/02/2022 | Away | Phil Foden | Everton FC | 82 | 0-0 → 0-1 | 0.52 | 0.67 | 0.95 | - |
| 06/03/2022 | Home | Kevin De Bruyne | Manchester United FC | 5 | 0-0 → 1-0 | 0.26 | 0.12 | 0.23 | Bernardo Silva |
| 06/03/2022 | Home | Kevin De Bruyne | Manchester United FC | 28 | 1-1 → 2-1 | 0.29 | 0.44 | 0.91 | - |
| 06/03/2022 | Home | Riyad Mahrez | Manchester United FC | 68 | 2-1 → 3-1 | 0.13 | 0.06 | 0.18 | Kevin De Bruyne |
| 06/03/2022 | Home | Riyad Mahrez | Manchester United FC | 91 | 3-1 → 4-1 | 0.00 | 0.42 | 0.89 | İlkay Gündoğan |
| 02/04/2022 | Away | Kevin De Bruyne | Burnley FC | 5 | 0-0 → 0-1 | 0.26 | 0.08 | 0.27 | Raheem Sterling |
| 02/04/2022 | Away | İlkay Gündoğan | Burnley FC | 25 | 0-1 → 0-2 | 0.18 | 0.23 | 0.07 | Raheem Sterling |
| 10/04/2022 | Home | Kevin De Bruyne | Liverpool FC | 5 | 0-0 → 1-0 | 0.26 | 0.02 | 0.38 | Bernardo Silva |
| 10/04/2022 | Home | Gabriel Jesus | Liverpool FC | 36 | 1-1 → 2-1 | 0.29 | 0.13 | 0.26 | João Cancelo |
| 20/04/2022 | Home | Riyad Mahrez | Brighton & Hove Albion FC | 53 | 0-0 → 1-0 | 0.35 | 0.25 | 0.66 | - |
| 20/04/2022 | Home | Phil Foden | Brighton & Hove Albion FC | 65 | 1-0 → 2-0 | 0.14 | 0.02 | 0.14 | Riyad Mahrez |
| 20/04/2022 | Home | Bernardo Silva | Brighton & Hove Albion FC | 82 | 2-0 → 3-0 | 0.01 | 0.09 | 0.23 | Kevin De Bruyne |
| 23/04/2022 | Home | Gabriel Jesus | Watford FC | 4 | 0-0 → 1-0 | 0.25 | 0.83 | 0.65 | Oleksandr Zinchenko |
| 23/04/2022 | Home | Gabriel Jesus | Watford FC | 23 | 1-0 → 2-0 | 0.18 | 0.54 | 0.59 | Kevin De Bruyne |
| 23/04/2022 | Home | Rodri | Watford FC | 34 | 2-1 → 3-1 | 0.18 | 0.03 | 0.41 | Gabriel Jesus |
| 23/04/2022 | Home | Gabriel Jesus | Watford FC | 49 | 3-1 → 4-1 | 0.05 | 0.79 | 0.98 | - |
| 23/04/2022 | Home | Gabriel Jesus | Watford FC | 53 | 4-1 → 5-1 | 0.01 | 0.24 | 0.27 | Kevin De Bruyne |
| 30/04/2022 | Away | Rodri | Leeds United FC | 13 | 0-0 → 0-1 | 0.26 | 0.28 | 0.54 | Phil Foden |
| 30/04/2022 | Away | Nathan Aké | Leeds United FC | 54 | 0-1 → 0-2 | 0.15 | 0.17 | 0.29 | Rúben Dias |
| 30/04/2022 | Away | Gabriel Jesus | Leeds United FC | 78 | 0-2 → 0-3 | 0.01 | 0.64 | 0.70 | Phil Foden |
| 30/04/2022 | Away | Fernandinho | Leeds United FC | 93 | 0-3 → 0-4 | 0.00 | 0.05 | 0.25 | - |
| 08/05/2022 | Home | Raheem Sterling | Newcastle United FC | 19 | 0-0 → 1-0 | 0.25 | 0.49 | 0.92 | João Cancelo |
| 08/05/2022 | Home | Aymeric Laporte | Newcastle United FC | 38 | 1-0 → 2-0 | 0.18 | 0.31 | 0.80 | - |
| 08/05/2022 | Home | Rodri | Newcastle United FC | 61 | 2-0 → 3-0 | 0.03 | 0.05 | 0.17 | Kevin De Bruyne |
| 08/05/2022 | Home | Phil Foden | Newcastle United FC | 90 | 3-0 → 4-0 | 0.00 | 0.56 | 0.92 | Oleksandr Zinchenko |
| 08/05/2022 | Home | Raheem Sterling | Newcastle United FC | 93 | 4-0 → 5-0 | 0.00 | 0.41 | 0.94 | Jack Grealish |
| 11/05/2022 | Away | Kevin De Bruyne | Wolverhampton Wanderers FC | 7 | 0-0 → 0-1 | 0.25 | 0.15 | 0.77 | Bernardo Silva |
| 11/05/2022 | Away | Kevin De Bruyne | Wolverhampton Wanderers FC | 16 | 1-1 → 1-2 | 0.25 | 0.09 | 0.76 | - |
| 11/05/2022 | Away | Kevin De Bruyne | Wolverhampton Wanderers FC | 24 | 1-2 → 1-3 | 0.18 | 0.08 | 0.38 | Raheem Sterling |
| 11/05/2022 | Away | Kevin De Bruyne | Wolverhampton Wanderers FC | 60 | 1-3 → 1-4 | 0.03 | 0.23 | 0.80 | - |
| 11/05/2022 | Away | Raheem Sterling | Wolverhampton Wanderers FC | 84 | 1-4 → 1-5 | 0.00 | 0.86 | 0.96 | - |
| 15/05/2022 | Away | Jack Grealish | West Ham United FC | 49 | 2-0 → 2-1 | 0.14 | 0.06 | 0.05 | Rodri |
| 15/05/2022 | Away | Vladimír Coufal (OG) | West Ham United FC | 69 | 2-1 → 2-2 | 0.31 | - | - | - |
| 22/05/2022 | Home | İlkay Gündoğan | Aston Villa FC | 76 | 0-2 → 1-2 | 0.08 | 0.34 | 0.62 | Raheem Sterling |
| 22/05/2022 | Home | Rodri | Aston Villa FC | 78 | 1-2 → 2-2 | 0.34 | 0.06 | 0.34 | Oleksandr Zinchenko |
| 22/05/2022 | Home | İlkay Gündoğan | Aston Villa FC | 81 | 2-2 → 3-2 | 0.50 | 0.84 | 0.95 | Kevin De Bruyne |