| 05/06/2021 | Home | Eder | São Paulo FC | 23 | 0-0 → 1-0 | 0.27 | 0.29 | 0.76 | Natanael |
| 05/06/2021 | Home | João Paulo Alves | São Paulo FC | 79 | 1-0 → 2-0 | 0.10 | 0.01 | 0.03 | Natanael |
| 20/06/2021 | Away | Gabriel Baralhas | Club Athletico Paranaense | 13 | 0-0 → 0-1 | 0.26 | 0.11 | 0.58 | - |
| 23/06/2021 | Home | Nathan Silva | Fluminense FC | 81 | 0-0 → 1-0 | 0.50 | 0.13 | 0.36 | Arthur |
| 01/07/2021 | Away | Marlon Freitas | Clube Atlético Mineiro | 46 | 3-0 → 3-1 | 0.04 | 0.24 | 0.81 | - |
| 04/07/2021 | Away | Lucão | Grêmio Foot-Ball Porto Alegrense | 55 | 0-0 → 0-1 | 0.36 | 0.41 | 0.68 | Luis Eduardo Marques dos Santos |
| 07/07/2021 | Home | Arthur | Sport Club do Recife | 51 | 0-1 → 1-1 | 0.26 | 0.08 | 0.52 | - |
| 11/07/2021 | Away | Zé Roberto | EC Juventude | 75 | 0-0 → 0-1 | 0.46 | 0.07 | 0.42 | Natanael |
| 21/07/2021 | Away | André Luis | Cuiabá Esporte Clube | 48 | 1-0 → 1-1 | 0.26 | 0.11 | 0.43 | - |
| 25/07/2021 | Away | Zé Roberto | Santos FC | 20 | 0-0 → 0-1 | 0.27 | 0.79 | 0.99 | - |
| 01/08/2021 | Home | Gabriel Baralhas | América FC (MG) | 20 | 0-1 → 1-1 | 0.24 | 0.07 | 0.13 | André Luis |
| 15/08/2021 | Away | Zé Roberto | Esporte Clube Bahia | 55 | 1-0 → 1-1 | 0.26 | 0.23 | 0.55 | Arnaldo |
| 15/08/2021 | Away | João Paulo Alves | Esporte Clube Bahia | 61 | 1-1 → 1-2 | 0.37 | 0.32 | 0.67 | - |
| 21/08/2021 | Home | João Paulo Alves | Associação Chapecoense de Futebol | 93 | 0-1 → 1-1 | 0.34 | 0.79 | 0.99 | - |
| 12/09/2021 | Home | Zé Roberto | SC Corinthians Paulista | 89 | 0-1 → 1-1 | 0.33 | 0.19 | 0.64 | Natanael |
| 19/09/2021 | Away | Matheus Barbosa | São Paulo FC | 71 | 2-0 → 2-1 | 0.09 | 0.21 | 0.13 | André Luis |
| 02/10/2021 | Away | Felipe (OG) | Fortaleza Esporte Clube | 18 | 0-0 → 0-1 | 0.26 | - | - | - |
| 02/10/2021 | Away | Gabriel Baralhas | Fortaleza Esporte Clube | 75 | 0-1 → 0-2 | 0.11 | 0.06 | 0.17 | - |
| 02/10/2021 | Away | Brian Montenegro | Fortaleza Esporte Clube | 95 | 0-2 → 0-3 | 0.00 | 0.13 | 0.48 | - |
| 17/10/2021 | Home | Janderson | Clube Atlético Mineiro | 65 | 0-1 → 1-1 | 0.28 | 0.19 | 0.73 | Marlon Freitas |
| 17/10/2021 | Home | Lucas Oliveira | Clube Atlético Mineiro | 81 | 1-1 → 2-1 | 0.50 | 0.14 | 0.63 | Janderson |
| 25/10/2021 | Home | Igor Cariús | Grêmio Foot-Ball Porto Alegrense | 44 | 0-0 → 1-0 | 0.31 | 0.04 | 0.66 | Eder |
| 25/10/2021 | Home | Marlon Freitas | Grêmio Foot-Ball Porto Alegrense | 72 | 1-0 → 2-0 | 0.12 | 0.79 | 0.99 | - |
| 20/11/2021 | Home | João Paulo Alves | Ceará SC | 55 | 0-1 → 1-1 | 0.26 | 0.13 | 0.27 | Arthur Henrique |
| 23/11/2021 | Home | Zé Roberto | EC Juventude | 62 | 0-0 → 1-0 | 0.37 | 0.32 | 0.86 | - |
| 29/11/2021 | Home | Marlon Freitas | Esporte Clube Bahia | 60 | 0-0 → 1-0 | 0.36 | 0.79 | 0.99 | - |
| 29/11/2021 | Home | Janderson | Esporte Clube Bahia | 93 | 1-1 → 2-1 | 0.63 | 0.17 | 0.56 | Lucão |
| 03/12/2021 | Away | Arthur Henrique | Associação Chapecoense de Futebol | 88 | 0-0 → 0-1 | 0.60 | 0.06 | 0.73 | Matheus Barbosa |
| 06/12/2021 | Away | Gabriel Baralhas | SC Internacional | 45 | 1-0 → 1-1 | 0.27 | 0.03 | 0.49 | Arnaldo |
| 06/12/2021 | Away | Janderson | SC Internacional | 47 | 1-1 → 1-2 | 0.32 | 0.84 | 0.95 | Arnaldo |
| 09/12/2021 | Home | Lucão | CR Flamengo | 82 | 0-0 → 1-0 | 0.52 | 0.11 | 0.35 | Marlon Freitas |
| 09/12/2021 | Home | Jonas | CR Flamengo | 92 | 1-0 → 2-0 | 0.02 | 0.32 | 0.20 | Marlon Freitas |